Drugging the undruggable
by targeting RNA
Every undruggable protein is encoded by an RNA.
Up to 85% of cellular proteins are considered undruggable today, including many key oncogenes and targets in neurodegeneration. By targeting undruggable genes at the RNA level, we are eliminating disease-causing proteins before they’re even made.
Wayfinder Biosciences is building a pipeline of small molecule assets for undruggable targets.
We discover selective small molecules that functionally modulate specific RNA targets.
Our platform combines proprietary experimental and AI/ML technologies to rapidly identify selective and functional RNA-targeting small molecules. Our technology is centered around Wayfinder’s RNA sensors, which are biophysically designed to generate a quantitative signal only when a small molecule selectively modulates the structure of the target RNA.
Partnering areas of interest: oncology, neurodegeneration, immunology, rare disease